環境材料・生物工学研究室

研究論文（2020年以降）

1. Honda Y, Takeuchi K, Hayakawa S, Koma D, Fujii H, Enhancement of nitrogenase activity in recombinant Escherichia coli by replacing upstream region of nif operon from Paenibacillus species, ChemBioChem, 27:e202500711, 2026.
2. Ohashi H, Koma D, Ohmoto T, Ohashi T, Satoh Y, Misaki R, Yamanaka H, Enhancing hydroxytyrosol stability via site-specific glucosylation, Carbohydrate Research, 556:109618, 2025.
3. Hirasawa T, Satoh Y, Koma D, Production of aromatic amino acids and their derivatives by Escherichia coli and Corynebacterium glutamicum, World Journal of Microbiology and Biotechnology, 41:65, 2025.
4. Shen N, Satoh Y, Koma D, Ohashi H, Ogasawara Y, Dairi T, Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli, Journal of Bioscience and Bioengineering, 137:115–123, 2024.
5. Ohashi H, Koma D, Yamanaka H, Ohmoto T, Enzymatic properties of UDP-glycosyltransferase 89B1 from radish and modulation of enzyme catalytic activity via loop region mutation, PLOS ONE, 19:e0299755, 2024.
6. Satoh Y, Fukui K, Koma D, Shen N, Lee TS, Engineered Escherichia coli platforms for tyrosine-derivative production from phenylalanine using phenylalanine hydroxylase and tetrahydrobiopterin-regeneration system, Biotechnology for Biofuels and Bioproducts, 16:115, 2023.
7. Koma D, Fujisawa M, Ohashi H, Yamanaka H, Moriyoshi K, Nagamori E, Ohmoto T, Production of 3-hydroxytyrosol from glucose by chromosomally engineered Escherichia coli by fed-batch cultivation in a jar fermenter, Journal of Agricultural and Food Chemistry, 71:9451–9459, 2023.
8. Fujita T, Nishi E, Koma D, Naito M, Hydroxytyrosol: Bioinspired nature-based adhesive motif with excellent chemical modifiability and stability, ACS Applied Polymer Materials, 5:3230–3234, 2023.
9. Koma D, Kishida T, Yoshida E, Ohashi H, Yamanaka H, Moriyoshi K, Nagamori E, Ohmoto T, Chromosome engineering to generate plasmid-free phenylalanine- and tyrosine-overproducing Escherichia coli strains that can be applied in the generation of aromatic-compound-producing bacteria, Applied and Environmental Microbiology, 86:e00525-20, 2020.
10. Ojima Y, Kawaguchi T, Fukui S, Kikuchi R, Terao K, Koma D, Ohmoto T, Azuma M, Promoted performance of microbial fuel cells using Escherichia coli cells with multiple-knockout of central metabolism genes, Bioprocess and Biosystems Engineering, 43:323–332, 2020.